SCHEMBL2463903

SCHEMBL2463903

[SiH3]N(c1ccccc1)[Si](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.33
NPSR1 Q6W5P4 1/20 0.33
ALOX15 P16050 1/20 0.33
TDP1 Q9NUW8 2/20 0.32
MAPT P10636 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
KDM4E B2RXH2 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
HTT P42858 1/20 0.32
USP2 O75604 1/20 0.31
EGFR P00533 1/20 0.31
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5604247 0.78 NPSR1 (0.34) ALDH1A1NPSR1ALOX15MAPTL3MBTL1
SCHEMBL10631629 0.78 NPSR1 (0.34) ALDH1A1NPSR1ALOX15TDP1KMT2A
SCHEMBL14369578 0.76 ALDH1A1 (0.35) ALDH1A1NPSR1ALOX15TDP1MAPT
SCHEMBL2549467 0.67
SCHEMBL8770403 0.67 ALDH1A1 (0.41) ALDH1A1NPSR1ALOX15TDP1MAPT
SCHEMBL17439066 0.67
SCHEMBL13900039 0.67 EGFR (0.31) EGFR
SCHEMBL328759 0.67 NPSR1 (0.33) NPSR1L3MBTL1MEN1KMT2AKDM4E
SCHEMBL3069583 0.67 ESR1 (0.37) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL2276954 0.67 ESR1 (0.37) ALDH1A1TDP1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9045347-B2 Stiochiometric silicon carbide fibers from thermo-chemically cured polysilazanes GENERAL ELECTRIC COMPANY (US) 2015-06-02 US claimed
US-20110212329-A1 STIOCHIOMETRIC SILICON CARBIDE FIBERS FROM THERMO-CHEMICALLY CURED POLYSILAZANES GENERAL ELECTRIC COMPANY 2011-09-01 US claimed
US-6313230-B1 HYDROGENATING CONJUGATED DIENE POLYMERS IN PRESENCE OF HYDROGEN AND A HYDROGENATION CATALYST FORMULATION COMPRISING TITANIUM COMPOUND, SILYL HYDRIDE COMPOUND, POLYSILOXANE, SILAZAN COMPOUND, AND METALLIC COMPOUND INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2001-11-06 US claimed
EP-2980221-B1 METHOD FOR COLLECTING ISOPRENE CONTAINED IN FERMENTED GAS, AND METHOD FOR PRODUCING PURIFIED ISOPRENE AJINOMOTO KK (JP) 2019-08-21 EP disclosed
US-10144684-B2 Method for collecting isoprenoid compound contained in fermented gas, and method for producing purified isoprenoid compound AJINOMOTO CO., INC. (JP) 2018-12-04 US disclosed
US-10144683-B2 Method for collecting isoprene contained in fermented gas, and method for producing purified isoprene AJINOMOTO CO., INC. (JP) 2018-12-04 US disclosed
EP-2980221-A1 METHOD FOR COLLECTING ISOPRENE CONTAINED IN FERMENTED GAS, AND METHOD FOR PRODUCING PURIFIED ISOPRENE Ajinomoto Co., Inc. (JP) 2016-02-03 EP disclosed
US-20160016867-A1 METHOD FOR COLLECTING ISOPRENE CONTAINED IN FERMENTED GAS, AND METHOD FOR PRODUCING PURIFIED ISOPRENE AJINOMOTO CO., INC. (JP) 2016-01-21 US disclosed
US-20160017375-A1 METHOD FOR COLLECTING ISOPRENOID COMPOUND CONTAINED IN FERMENTED GAS, AND METHOD FOR PRODUCING PURIFIED ISOPRENOID COMPOUND AJINOMOTO CO., INC. (JP) 2016-01-21 US disclosed
US-9045347-B2 Stiochiometric silicon carbide fibers from thermo-chemically cured polysilazanes GENERAL ELECTRIC COMPANY (US) 2015-06-02 US disclosed
US-20110212329-A1 STIOCHIOMETRIC SILICON CARBIDE FIBERS FROM THERMO-CHEMICALLY CURED POLYSILAZANES GENERAL ELECTRIC COMPANY 2011-09-01 US disclosed
WO-2009034169-A1 PROCESSES FOR THE PREPARATION OF THE ALPHA CRYSTAL POLYMORPH OF METAL PHTHALOCYANINES UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (IE) 2009-03-19 WO disclosed
US-4772494-A Method of spinning fibers and coating from an organopolysilazane composition containing free radical generators and capable of being crosslinked by an energy input RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1988-09-20 US disclosed
US-4722988-A Organopolysilazane composition containing free radical generators and capable of being crosslinked by an energy input RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1988-02-02 US disclosed