SCHEMBL5604247

SCHEMBL5604247

O[Si](O)(c1ccccc1)N([SiH3])c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.34
ALDH1A1 P00352 3/20 0.32
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31
MEN1 O00255 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
KMT2A Q03164 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2463903 0.78 ALDH1A1 (0.33) NPSR1ALDH1A1ESR1ESR2MEN1
SCHEMBL10631629 0.73 NPSR1 (0.34) NPSR1ALDH1A1KMT2ASMN1; SMN2ALOX15
SCHEMBL2456201 0.64 ESR1 (0.39) ALDH1A1ESR1ESR2MAPTALOX15
SCHEMBL7871195 0.64 ESR1 (0.39) ALDH1A1ESR1ESR2MAPTALOX15
SCHEMBL11904130 0.64 ESR1 (0.39) ALDH1A1ESR1ESR2ALOX15
SCHEMBL2549467 0.63
SCHEMBL8770403 0.63 ALDH1A1 (0.41) NPSR1ALDH1A1MEN1GAAMAPT
SCHEMBL49494 0.63 ESR1 (0.42) ALDH1A1ESR1ESR2MAPTHPGD
SCHEMBL49883 0.63 ESR1 (0.42) ALDH1A1ESR1ESR2MAPTHPGD
SCHEMBL273507 0.63 ESR1 (0.42) NPSR1ALDH1A1ESR1ESR2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0997482-B1 MODIFIED CYCLOOLEFIN ADDITION POLYMER AND CURABLE RESIN COMPOSITION CONTAINING THE SAME NIPPON ZEON CO (JP) 2007-01-17 EP disclosed
US-6346581-B1 CURABLE COMPOSITION COMPRISING POLYMER OBTAINED BY INTRODUCING FUNCTIONAL GROUP INTO CYCLOOLEFIN ADDITION POLYMER CONSISTING OF UNITS DERIVED FROM CYCLOOLEFIN MONOMERS WITH AND WITHOUT SIDE CHAIN HAVING 4 OR MORE CARBONS, HARDENING AGENT NIPPON ZEON CO., LTD (JP) 2002-02-12 US disclosed
EP-0997482-A1 MODIFIED CYCLOOLEFIN ADDITION POLYMER AND CURABLE RESIN COMPOSITION CONTAINING THE SAME NIPPON ZEON CO., LTD. (JP) 2000-05-03 EP disclosed