Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24639249 | 0.78 | LTA4H (0.33) | KRASTIPARP | |
| SCHEMBL24640616 | 0.78 | KRAS (0.32) | KRASTIPARP | |
| SCHEMBL24639280 | 0.78 | LTA4H (0.33) | KRASTIPARP | |
| SCHEMBL31245220 | 0.76 | TIPARP (0.48) | TIPARP | |
| SCHEMBL24640780 | 0.75 | LTA4H (0.36) | KRAS | |
| SCHEMBL24640311 | 0.74 | TIPARP (0.34) | KRASTIPARP | |
| SCHEMBL24640825 | 0.71 | TIPARP (0.48) | KRASTIPARP | |
| SCHEMBL31244967 | 0.71 | TIPARP (0.48) | TIPARP | |
| SCHEMBL31245225 | 0.69 | KRAS (0.41) | KRASTIPARP | |
| SCHEMBL24640611 | 0.68 | TIPARP (0.34) | KRASTIPARP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022170974-A1 | TRICYCLIC DERIVATIVES USEFUL AS PARP7 INHIBITORS | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-08-18 | — | — | WO | disclosed |