Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26958276 | 0.80 | HRH3 (0.33) | HRH3 | |
| SCHEMBL24640317 | 0.79 | TIPARP (0.33) | HRH3NR1H2NR1H3GSK3B | |
| SCHEMBL24639861 | 0.77 | HRH3 (0.36) | HRH3NR1H2NR1H3 | |
| SCHEMBL31244742 | 0.75 | HTR2C (0.36) | — | |
| SCHEMBL24639880 | 0.74 | HRH3 (0.31) | HRH3 | |
| SCHEMBL24640313 | 0.72 | SOS1 (0.36) | HRH3 | |
| SCHEMBL24639879 | 0.72 | HRH3 (0.31) | HRH3 | |
| SCHEMBL24639851 | 0.70 | HRH3 (0.36) | HRH3NR1H2NR1H3 | |
| SCHEMBL24639871 | 0.68 | HRH3 (0.37) | HRH3NR1H2NR1H3 | |
| SCHEMBL24639833 | 0.67 | NR1H2 (0.37) | HRH3NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022170974-A1 | TRICYCLIC DERIVATIVES USEFUL AS PARP7 INHIBITORS | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-08-18 | — | — | WO | disclosed |