SCHEMBL2464047

SCHEMBL2464047

C=C(C)C(=O)CC(=C)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.44
HSD17B10 Q99714 1/20 0.44
TET2 Q6N021 5/20 0.38
ALDH1A1 P00352 1/20 0.36
TET3 O43151 1/20 0.36
TET1 Q8NFU7 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
GRIK1 P39086 1/20 0.34
GRIK2 Q13002 1/20 0.34
GRM1 Q13255 1/20 0.34
GRM2 Q14416 1/20 0.34
TGFBR1 P36897 1/20 0.34
FFAR3 O14843 1/20 0.30
LCK P06239 1/20 0.30
FYN P06241 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL8425144 0.97 ALOX15 (0.43) ALOX15HSD17B10TET2ALDH1A1TET3
Acrylic Acid SCHEMBL8426415 0.82 ALOX15 (0.55) ALOX15HSD17B10ALDH1A1
SCHEMBL1300526 0.80 ALOX15 (0.50) ALOX15HSD17B10TET2TET3TET1
SCHEMBL16140641 0.80 ALDH1A1 (0.45) HSD17B10ALDH1A1TDP1TGFBR1
Itaconate SCHEMBL5429101 0.79 ALOX15 (0.62) ALOX15HSD17B10TET2ALDH1A1TET3
Itaconate SCHEMBL2945767 0.79 ALOX15 (0.62) ALOX15HSD17B10TET2ALDH1A1TET3
Itaconate SCHEMBL31425252 0.79 ALOX15 (0.62) ALOX15HSD17B10TET2ALDH1A1TET3
SCHEMBL6656723 0.78
SCHEMBL3459289 0.78
SCHEMBL472577 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1996633-B1 MOLECULAR IMPRINTINGS FOR RECOGNITION IN AQUEOUS MEDIA, METHODS FOR PREPARING SAME AND USES THEREOF POLYINTELL (FR) 2010-05-12 EP claimed
US-8227379-B2 Thermosensitive recording medium and recording method RICOH COMPANY, LTD. (JP) 2012-07-24 US disclosed
EP-2093072-B1 Thermosensitive recording medium and recording method RICOH CO LTD (JP) 2011-09-07 EP disclosed
US-20090215622-A1 THERMOSENSITIVE RECORDING MEDIUM AND RECORDING METHOD RICOH COMPANY, LTD. (JP) 2009-08-27 US disclosed
EP-2093072-A1 Thermosensitive recording medium and recording method Ricoh Company, Limited (JP) 2009-08-26 EP disclosed
EP-0933682-A2 Polymers comprising N-substituted maleimide units and their use in radiation-sensitive compositions Agfa-Gevaert AG (DE) 1999-08-04 EP disclosed