Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 3/20 | 0.37 |
| ▸ | HRH1 | P35367 | 3/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14751225 | 0.84 | CA1 (0.39) | TSHRKMT2ACA1CA2CA7 | |
| SCHEMBL14738147 | 0.84 | CA1 (0.39) | TSHRKMT2ACA1CA2CA7 | |
| SCHEMBL14738146 | 0.84 | CA1 (0.39) | TSHRKMT2ACA1CA2CA7 | |
| SCHEMBL25283470 | 0.83 | CTSL (0.52) | KMT2AMEN1ALDH1A1CTSLMAPK1 | |
| SCHEMBL25243646 | 0.83 | CTSL (0.52) | KMT2AMEN1ALDH1A1CTSLMAPK1 | |
| SCHEMBL18212469 | 0.80 | CA1 (0.42) | TSHRKMT2ACA1CA2CA7 | |
| SCHEMBL7510900 | 0.78 | CTSK (0.48) | CA1CA2CA7HDAC4HDAC6 | |
| SCHEMBL18534563 | 0.78 | CTSK (0.48) | CA1CA2CA7HDAC4HDAC6 | |
| SCHEMBL12420756 | 0.78 | CTSK (0.48) | CA1CA2CA7HDAC4HDAC6 | |
| SCHEMBL18215100 | 0.77 | HDAC4 (0.43) | TSHRKMT2AMEN1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022170974-A1 | TRICYCLIC DERIVATIVES USEFUL AS PARP7 INHIBITORS | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-08-18 | — | — | WO | disclosed |