SCHEMBL2464113

SCHEMBL2464113

CCCCCCCCCCC=Cc1cc(Br)c(C=CCCCCCCCCCC)cc1Br

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FAAH O00519 2/20 0.41
TRPV1 Q8NER1 1/20 0.41
MGLL Q99685 1/20 0.39
CYSLTR2 Q9NS75 2/20 0.38
CYSLTR1 Q9Y271 2/20 0.38
PDE5A O76074 1/20 0.38
CCR5 P51681 4/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2495389 1.00 FAAH (0.41) FAAHTRPV1MGLLCYSLTR2CYSLTR1
SCHEMBL9559868 0.80 CYSLTR2 (0.47) FAAHTRPV1MGLLCYSLTR2CYSLTR1
SCHEMBL9834665 0.80 CYSLTR2 (0.47) FAAHTRPV1MGLLCYSLTR2CYSLTR1
SCHEMBL10651318 0.80 CYSLTR2 (0.47) FAAHTRPV1MGLLCYSLTR2CYSLTR1
SCHEMBL9559869 0.80 CYSLTR2 (0.47) FAAHTRPV1MGLLCYSLTR2CYSLTR1
SCHEMBL8496315 0.80 CYSLTR2 (0.47) FAAHTRPV1MGLLCYSLTR2CYSLTR1
SCHEMBL10383726 0.80 CYSLTR2 (0.47) FAAHTRPV1MGLLCYSLTR2CYSLTR1
SCHEMBL10383727 0.80 CYSLTR2 (0.47) FAAHTRPV1MGLLCYSLTR2CYSLTR1
SCHEMBL10651322 0.80 CYSLTR2 (0.47) FAAHTRPV1MGLLCYSLTR2CYSLTR1
SCHEMBL10520046 0.80 CYSLTR2 (0.47) FAAHTRPV1MGLLCYSLTR2CYSLTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9073938-B2 Method for producing aromatic compound NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2015-07-07 US disclosed
EP-2147923-B1 METHOD FOR PRODUCING AROMATIC COMPOUND NIPPON KAYAKU KK (JP) 2014-06-04 EP disclosed
EP-2371829-A1 Method for producing benzo-trithiophene or benzo-triselenophene derivatives Nippon Kayaku Kabushiki Kaisha (JP) 2011-10-05 EP disclosed
US-20100137617-A1 METHOD FOR PRODUCING AROMATIC COMPOUND NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2010-06-03 US disclosed
EP-2147923-A1 METHOD FOR PRODUCING AROMATIC COMPOUND Nippon Kayaku Kabushiki Kaisha (JP) 2010-01-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100137617-A1 METHOD FOR PRODUCING AROMATIC COMPOUND SCLY, TYR, CBS FAAH 3949/4885TRPV1 2508/4885MGLL 3844/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.