Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 12/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 12/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.37 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.37 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26522477 | 0.83 | SIGMAR1 (0.40) | KDM4CKDM5AALDH1A1 | |
| SCHEMBL20732425 | 0.80 | KDM4A (0.40) | KDM4AKDM4CKDM5AKDM7APHF8 | |
| SCHEMBL805213 | 0.80 | KDM4A (0.40) | KDM4AKDM4CKDM5AKDM7APHF8 | |
| SCHEMBL24642454 | 0.80 | KDM4A (0.40) | KDM4AKDM4CKDM5AKDM7APHF8 | |
| SCHEMBL2038707 | 0.79 | FOLH1 (0.51) | CPB2FOLH1 | |
| SCHEMBL29193624 | 0.79 | FOLH1 (0.51) | CPB2FOLH1 | |
| SCHEMBL8171418 | 0.79 | KDM4A (0.39) | KDM4AKDM4CKDM5AKDM7APHF8 | |
| SCHEMBL22717112 | 0.77 | SMN1; SMN2 (0.48) | KDM4AKDM4CKDM5AKDM7APHF8 | |
| SCHEMBL22717113 | 0.77 | SMN1; SMN2 (0.48) | KDM4AKDM4CKDM5AKDM7APHF8 | |
| SCHEMBL26497527 | 0.74 | ZDHHC7 (0.36) | KDM4AKDM4CKDM5AKDM7APHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022170971-A1 | BIOACTIVE SUBSTANCE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州宜联生物医药有限公司 | 2022-08-18 | — | — | WO | disclosed |