Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 12/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 12/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.40 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.40 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20732425 | 1.00 | KDM4A (0.40) | KDM4AKDM4CKDM5AKDM7APHF8 | |
| SCHEMBL25657481 | 0.86 | UTS2R (0.33) | ALDH1A1FOLH1 | |
| SCHEMBL24157900 | 0.85 | ALDH1A1 (0.37) | KDM4AKDM4CKDM5AKDM7APHF8 | |
| SCHEMBL19381471 | 0.85 | ALDH1A1 (0.37) | KDM4AKDM4CKDM5AKDM7APHF8 | |
| SCHEMBL24642454 | 0.85 | KDM4A (0.40) | KDM4AKDM4CKDM5AKDM7APHF8 | |
| SCHEMBL25358066 | 0.84 | FOLH1 (0.38) | ALDH1A1FOLH1 | |
| SCHEMBL25358064 | 0.84 | FOLH1 (0.38) | ALDH1A1FOLH1 | |
| SCHEMBL8171418 | 0.83 | KDM4A (0.39) | KDM4AKDM4CKDM5AKDM7APHF8 | |
| SCHEMBL18373090 | 0.83 | ALDH1A1 (0.36) | KDM4AKDM4CKDM5AKDM7APHF8 | |
| SCHEMBL27383905 | 0.82 | BHMT (0.42) | KDM4AKDM4CKDM5APHF8FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120245040-A1 | METHODS FOR SYNTHESIS OF ENCODED LIBRARIES | GLAXOSMITHKLINE (US) | 2012-09-27 | — | — | US | disclosed |
| US-20120071329-A1 | METHODS FOR IDENTIFYING COMPOUNDS OF INTEREST USING ENCODED LIBRARIES | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | US | disclosed |
| US-20110251089-A1 | METHODS FOR SYNTHESIS OF ENCODED LIBRARIES | GLAXOSMITHKLINE (US) | 2011-10-13 | — | — | US | disclosed |
| US-7989395-B2 | Methods for identifying compounds of interest using encoded libraries | GLAXOSMITHKLINE LLC (US) | 2011-08-02 | — | — | US | disclosed |
| US-7972992-B2 | Solid phase synthesis | PRAECIS PHARMACEUTICALS, INC. (US) | 2011-07-05 | — | — | US | disclosed |
| US-7935658-B2 | Methods for synthesis of encoded libraries | PRAECIS PHARMACEUTICALS, INC. (US) | 2011-05-03 | — | — | US | disclosed |
| US-20090062147-A1 | Methods for synthesis of encoded libraries | PRAECIS PHARMACEUTICALS INCORPORATED (US) | 2009-03-05 | — | — | US | disclosed |
| WO-2002007756-A1 | MuO-CONOPEPTIDES AND THEIR USE AS LOCAL ANESTHETICS | COGNETIX, INC. (US) | 2002-01-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120245040-A1 | METHODS FOR SYNTHESIS OF ENCODED LIBRARIES | RNGTT, DTYMK, DUT | KDM4A 3412/4885KDM4C 2839/4885KDM5A 3150/4885 |
| US-20110251089-A1 | METHODS FOR SYNTHESIS OF ENCODED LIBRARIES | RNGTT, DTYMK, DUT | KDM4A 3412/4885KDM4C 2839/4885KDM5A 3150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.