Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GHSR | Q92847 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5530162 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNASIGMAR1CPB2 | |
| SCHEMBL24642319 | 0.77 | SIGMAR1 (0.43) | LMNACHRM2CHRM1CYP1A2CYP2D6 | |
| SCHEMBL24642553 | 0.77 | SIGMAR1 (0.43) | SMN1; SMN2LMNACYP3A4CYP1A2CYP2D6 | |
| SCHEMBL24642520 | 0.75 | LMNA (0.44) | LMNACYP1A2CYP2D6SIGMAR1ALDH1A1 | |
| SCHEMBL15384058 | 0.75 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNACHRM1ADRA1ADRD3 | |
| SCHEMBL19753551 | 0.75 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNACHRM1ADRA1ADRD3 | |
| SCHEMBL12482729 | 0.74 | LMNA (0.41) | SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL9181567 | 0.74 | CPB2 (0.55) | CPB2 | |
| SCHEMBL9181564 | 0.74 | CPB2 (0.55) | CPB2 | |
| SCHEMBL5130749 | 0.73 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022170971-A1 | BIOACTIVE SUBSTANCE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州宜联生物医药有限公司 | 2022-08-18 | — | — | WO | disclosed |