Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.43 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24645249 | 0.83 | HTRA1 (0.45) | GPR119HTRA1UCHL1CYP1A2POLB | |
| SCHEMBL24645260 | 0.80 | HTRA1 (0.43) | GPR119HTRA1HSD17B10UCHL1CYP1A2 | |
| SCHEMBL24645494 | 0.80 | HTRA1 (0.45) | GPR119HTRA1HSD17B10UCHL1CYP1A2 | |
| SCHEMBL24645453 | 0.80 | HTRA1 (0.48) | GPR119HTRA1KDM4E | |
| SCHEMBL7898459 | 0.80 | GPR119 (0.54) | GPR119USP30KDM4E | |
| SCHEMBL24645264 | 0.80 | MMP2 (0.41) | GPR119HTRA1HSD17B10UCHL1CYP1A2 | |
| SCHEMBL23452522 | 0.79 | HTRA1 (0.49) | GPR119HTRA1HSD17B10UCHL1CYP1A2 | |
| SCHEMBL24645322 | 0.79 | HTRA1 (0.49) | GPR119HTRA1HSD17B10UCHL1CYP1A2 | |
| SCHEMBL24645467 | 0.77 | GPR119 (0.39) | GPR119HTRA1HSD17B10UCHL1CYP1A2 | |
| SCHEMBL25364473 | 0.76 | HTRA1 (0.38) | GPR119HTRA1HSD17B10UCHL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220305011-A1 | FACTOR XIIA INHIBITORS | UNIVERSITY OF LEEDS (GB) | 2022-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220305011-A1 | FACTOR XIIA INHIBITORS | F11, F13B, F12 | GPR119 4204/4885HTRA1 129/4885HSD17B10 1103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.