Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | FGF2 | P09038 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3938395 | 0.77 | CYP1A2 (0.47) | POLBALDH1A1HTTHPGDSMN1; SMN2 | |
| SCHEMBL6546386 | 0.74 | TET2 (0.40) | POLBALDH1A1HTTSMN1; SMN2FGF2 | |
| SCHEMBL6546396 | 0.74 | TET2 (0.40) | POLBALDH1A1HTTSMN1; SMN2FGF2 | |
| SCHEMBL6547554 | 0.73 | POLB (0.39) | POLBALDH1A1HTTHPGDSMN1; SMN2 | |
| SCHEMBL6547560 | 0.73 | POLB (0.39) | POLBALDH1A1HTTHPGDSMN1; SMN2 | |
| SCHEMBL6789915 | 0.72 | SLC1A3 (0.39) | — | |
| SCHEMBL6787830 | 0.72 | SLC1A3 (0.39) | — | |
| SCHEMBL7079225 | 0.71 | ALDH1A1 (0.41) | POLBALDH1A1HTTHPGDSMN1; SMN2 | |
| SCHEMBL10584872 | 0.70 | HTT (0.44) | POLBALDH1A1HTTHPGDSMN1; SMN2 | |
| SCHEMBL6546698 | 0.70 | MMP2 (0.36) | POLBALDH1A1HTTHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1355676-B1 | METHOD OF PROTECTING THERAPEUTIC COMPOSITIONS FROM HOST-MEDIATED INACTIVATION | UNIV SOUTH CAROLINA (US) | 2011-10-05 | — | — | EP | claimed |