SCHEMBL24645804

SCHEMBL24645804

COC1O[C@H](CN)[C@H]2OC(C)(C)O[C@@H]12

nearest known ligand 0.43

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.36
CA1 P00915 1/20 0.36
CA9 Q16790 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10118086 1.00 CA2 (0.36) CA2CA1CA9
SCHEMBL10135572 1.00 CA2 (0.36) CA2CA1CA9
SCHEMBL6920159 1.00 CA2 (0.36) CA2CA1CA9
SCHEMBL7301263 1.00 CA2 (0.36) CA2CA1CA9
SCHEMBL18517496 0.86 G6PD (0.35) CA2CA1CA9
SCHEMBL18805837 0.86 G6PD (0.35) CA2CA1CA9
SCHEMBL8322168 0.83 CA2 (0.34) CA2CA1CA9
SCHEMBL17170416 0.83 CA2 (0.34) CA2CA1CA9
SCHEMBL21449039 0.83 CA2 (0.34) CA2CA1CA9
SCHEMBL2621335 0.83 CA2 (0.34) CA2CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240092819-A1 NOVEL LIGANDS FOR ASIALOGLYCOPROTEIN RECEPTOR SANOFI SA (FR) 2024-03-21 US disclosed
EP-4232455-A2 NOVEL LIGANDS FOR ASIALOGLYCOPROTEIN RECEPTOR Sanofi (FR) 2023-08-30 EP disclosed
US-20220259253-A1 CD73 INHIBITORS ORIC PHARMACEUTICALS, INC. 2022-08-18 US disclosed
WO-2022084331-A2 NOVEL LIGANDS FOR ASIALOGLYCOPROTEIN RECEPTOR SANOFI (FR) 2022-04-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220259253-A1 CD73 INHIBITORS ENTPD5, NT5E, ENTPD1 CA2 2826/4885CA1 2856/4885CA9 1882/4885
US-20240092819-A1 NOVEL LIGANDS FOR ASIALOGLYCOPROTEIN RECEPTOR ASGR1, HAVCR2, SIGLEC7 CA2 4829/4885CA1 4710/4885CA9 4667/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.