SCHEMBL7301263

SCHEMBL7301263

CO[C@@H]1O[C@H](CN)[C@H]2OC(C)(C)O[C@@H]12

nearest known ligand 0.43

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.36
CA1 P00915 1/20 0.36
CA9 Q16790 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10118086 1.00 CA2 (0.36) CA2CA1CA9
SCHEMBL24645804 1.00 CA2 (0.36) CA2CA1CA9
SCHEMBL10135572 1.00 CA2 (0.36) CA2CA1CA9
SCHEMBL6920159 1.00 CA2 (0.36) CA2CA1CA9
SCHEMBL18517496 0.86 G6PD (0.35) CA2CA1CA9
SCHEMBL18805837 0.86 G6PD (0.35) CA2CA1CA9
SCHEMBL8322168 0.83 CA2 (0.34) CA2CA1CA9
SCHEMBL17170416 0.83 CA2 (0.34) CA2CA1CA9
SCHEMBL21449039 0.83 CA2 (0.34) CA2CA1CA9
SCHEMBL2621335 0.83 CA2 (0.34) CA2CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220033428-A1 LARGE SCALE PREPARATION OF PSEUDO-TRISACCHARIDE AMINOGLYCOSIDES AND OF INTERMEDIATES THEREOF ELOXX PHARMACEUTICALS LTD. (IL) 2022-02-03 US disclosed
US-11136345-B2 Large scale preparation of pseudo-trisaccharide aminoglycosides and of intermediates thereof ELOXX PHARMACEUTICALS LTD. (IL) 2021-10-05 US disclosed
US-20120040897-A1 NOVEL DERIVATIVES OF ACYL CYANOPYRROLIDINES SUN PHARMA ADVANCED RESEARCH COMPANY LTD. (IN) 2012-02-16 US disclosed
US-20120040897-A1 NOVEL DERIVATIVES OF ACYL CYANOPYRROLIDINES SUN PHARMA ADVANCED RESEARCH COMPANY LTD. (IN) 2012-02-16 US disclosed
WO-2009116067-A2 NOVEL DERIVATIVES OF ACYL CYANOPYRROLIDINES SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED (IN) 2009-09-24 WO disclosed
EP-0337714-A2 HIV protease inhibitors useful for the treatment of aids MERCK & CO. INC. (US) 1989-10-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120040897-A1 NOVEL DERIVATIVES OF ACYL CYANOPYRROLIDINES NR1D2, STARD10, NR1D1 CA2 894/4885CA1 2022/4885CA9 1253/4885
US-11136345-B2 Large scale preparation of pseudo-trisaccharide aminoglycosides and of intermediates thereof OSTC, TREH, GPI CA2 4701/4885CA1 4183/4885CA9 2825/4885
US-20220033428-A1 LARGE SCALE PREPARATION OF PSEUDO-TRISACCHARIDE AMINOGLYCOSIDES AND OF INTERMEDIATES THEREOF OSTC, TREH, GPI CA2 4701/4885CA1 4183/4885CA9 2825/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.