Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18511473 | 0.84 | ESR1 (0.46) | SLC6A3SLC6A4HIF1AADRB1ADRA1A | |
| SCHEMBL14452294 | 0.84 | ADRB1 (0.42) | SLC6A3SLC6A4HIF1AADRB1ADRA1A | |
| SCHEMBL21688292 | 0.83 | ESR1 (0.44) | SLC6A3SLC6A4HIF1AADRB1ADRA1A | |
| SCHEMBL25474388 | 0.81 | SLC6A2 (0.43) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL25474391 | 0.81 | SLC6A2 (0.43) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL25474483 | 0.81 | SLC6A2 (0.43) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL3659348 | 0.80 | FFAR1 (0.59) | OPRD1OPRK1ALDH1A1KYNUFFAR1 | |
| SCHEMBL21670728 | 0.80 | FFAR1 (0.41) | SLC6A3SLC6A4HIF1AADRB1ADRA1A | |
| SCHEMBL3657592 | 0.80 | FFAR1 (0.59) | OPRD1OPRK1ALDH1A1KYNUFFAR1 | |
| SCHEMBL29374616 | 0.80 | FFAR1 (0.59) | OPRD1OPRK1ALDH1A1KYNUFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250276989-A1 | GPR40 AGONISTS | KALLYOPE, INC. | 2025-09-04 | — | — | US | disclosed |
| US-12264171-B2 | GPR40 agonists | KALLYOPE, INC. (US) | 2025-04-01 | — | — | US | disclosed |
| US-20230151037-A1 | GPR40 AGONISTS | KALLYOPE, INC. | 2023-05-18 | — | — | US | disclosed |
| US-20230151037-A1 | GPR40 AGONISTS | KALLYOPE, INC. | 2023-05-18 | — | — | US | disclosed |
| US-20230151037-A1 | GPR40 AGONISTS | KALLYOPE, INC. | 2023-05-18 | — | — | US | disclosed |
| CN-115867536-A | GPR40 agonists | 卡尔优普公司 | 2023-03-28 | — | — | CN | disclosed |
| US-20220289772-A1 | GPR40 AGONISTS | KALLYOPE, INC. | 2022-09-15 | — | — | US | disclosed |
| US-20220289772-A1 | GPR40 AGONISTS | KALLYOPE, INC. | 2022-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12264171-B2 | GPR40 agonists | GPR119, GPR65, GLP1R | SLC6A3 1288/4885SLC6A4 596/4885SLC6A2 1148/4885 |
| US-20220289772-A1 | GPR40 AGONISTS | GPR119, GPR65, GLP1R | SLC6A3 1288/4885SLC6A4 596/4885SLC6A2 1148/4885 |
| US-20250276989-A1 | GPR40 AGONISTS | GPR119, GPR65, GLP1R | SLC6A3 1288/4885SLC6A4 596/4885SLC6A2 1148/4885 |
| US-20230151037-A1 | GPR40 AGONISTS | GPR119, GPR65, GLP1R | SLC6A3 1288/4885SLC6A4 596/4885SLC6A2 1148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.