Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17911614 | 0.88 | KCNA3 (0.48) | ALDH1A1SMN1; SMN2MAPTTSHRKCNA3 | |
| SCHEMBL5375466 | 0.86 | LTA4H (0.68) | TSHRLTA4HKCNA3PLA2G2A | |
| SCHEMBL7285169 | 0.82 | MAOB (0.62) | — | |
| SCHEMBL27950450 | 0.82 | PRSS1 (0.53) | TSHRKMT2AKCNA3 | |
| SCHEMBL3950956 | 0.82 | KCNA3 (0.71) | ALDH1A1LTA4HKCNA3PLA2G2A | |
| SCHEMBL71797 | 0.82 | KCNA3 (0.71) | ALDH1A1LTA4HKCNA3PLA2G2A | |
| SCHEMBL12967962 | 0.81 | LTA4H (0.79) | KDM4EALDH1A1TDP1LMNASMN1; SMN2 | |
| SCHEMBL8778562 | 0.81 | KDM4E (0.56) | KDM4EALDH1A1TDP1LMNASMN1; SMN2 | |
| SCHEMBL13886635 | 0.81 | LTA4H (0.61) | KDM4EALDH1A1TDP1LMNASMN1; SMN2 | |
| SCHEMBL4221034 | 0.81 | LTA4H (0.55) | LTA4HKCNA3FFAR1FFAR4MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220378744-A1 | COMPOUNDS FOR TREATING PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) MEDIATED DISEASES OR CONDITIONS | MEDIPURE PHARMACEUTICALS INC (CA) | 2022-12-01 | — | — | US | disclosed |
| WO-2022221960-A1 | COMPOUNDS FOR TREATING PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) MEDIATED DISEASES OR CONDITIONS | Medipure Pharmaceuticals Inc. (CA) | 2022-10-27 | — | — | WO | disclosed |
| WO-2022221960-A1 | COMPOUNDS FOR TREATING PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) MEDIATED DISEASES OR CONDITIONS | Medipure Pharmaceuticals Inc. (CA) | 2022-10-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220378744-A1 | COMPOUNDS FOR TREATING PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) MEDIATED DISEASES OR CONDITIONS | PPARG, PPARA, PPARD | KDM4E 3227/4885ALDH1A1 2031/4885TDP1 3826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.