Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6470278 | 0.86 | LTA4H (0.68) | TSHRLTA4HKCNA3PLA2G2A | |
| SCHEMBL8778600 | 0.86 | TDP1 (0.54) | KDM4ETDP1SMN1; SMN2MAPTHTT | |
| SCHEMBL8778594 | 0.82 | TSHR (0.42) | KDM4EALDH1A1TDP1LMNASMN1; SMN2 | |
| SCHEMBL2091885 | 0.82 | KDM4E (0.51) | KDM4EALDH1A1TDP1LMNASMN1; SMN2 | |
| SCHEMBL73327 | 0.82 | KCNA3 (0.71) | ALDH1A1LTA4HKCNA3PLA2G2A | |
| SCHEMBL24648592 | 0.81 | KDM4E (0.56) | KDM4EALDH1A1TDP1LMNASMN1; SMN2 | |
| SCHEMBL12967962 | 0.81 | LTA4H (0.79) | KDM4EALDH1A1TDP1LMNASMN1; SMN2 | |
| SCHEMBL13886635 | 0.81 | LTA4H (0.61) | KDM4EALDH1A1TDP1LMNASMN1; SMN2 | |
| SCHEMBL11705181 | 0.81 | KDM4E (0.59) | KDM4EALDH1A1TDP1LMNASMN1; SMN2 | |
| SCHEMBL8539801 | 0.81 | LTA4H (0.55) | LTA4HKCNA3FFAR1FFAR4MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574355-B1 | Phosphinyloxy propanaminium inner salt derivatives | CIBA GEIGY AG (CH) | 1997-08-13 | — | — | EP | claimed |
| EP-0574355-A1 | Phosphinyloxy propanaminium inner salt derivatives | SANDOZ LTD. (CH) | 1993-12-15 | — | — | EP | claimed |