Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10684344 | 0.86 | ALDH1A1 (0.43) | TSHRALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL8348874 | 0.82 | NOS3 (0.37) | NOS3NOS1NOS2CA1CA2 | |
| SCHEMBL6983472 | 0.81 | SLC1A1 (0.39) | NOS3NOS1NOS2CA1CA2 | |
| SCHEMBL23419880 | 0.81 | SLC1A1 (0.39) | NOS3NOS1NOS2CA1CA2 | |
| SCHEMBL8348754 | 0.81 | SLC1A1 (0.39) | NOS3NOS1NOS2CA1CA2 | |
| SCHEMBL11776470 | 0.80 | SMN1; SMN2 (0.42) | TSHRALDH1A1CA1CA2SLC1A1 | |
| SCHEMBL15707495 | 0.79 | ALDH1A1 (0.44) | TSHRALDH1A1SLC1A1 | |
| Hydrochloric Acid SCHEMBL29262798 | 0.79 | SLC1A1 (0.38) | ALDH1A1NOS3NOS1NOS2CA1 | |
| Hydrochloric Acid SCHEMBL29262795 | 0.79 | SLC1A1 (0.38) | ALDH1A1NOS3NOS1NOS2CA1 | |
| SCHEMBL18593302 | 0.79 | TSHR (0.38) | TSHRALDH1A1NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220362396-A1 | AMINO-PYRAZINECARBOXAMIDE COMPOUNDS, CONJUGATES, AND USES THEREOF | SILVERBACK THERAPEUTICS, INC. | 2022-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220362396-A1 | AMINO-PYRAZINECARBOXAMIDE COMPOUNDS, CONJUGATES, AND USES THEREOF | TGFBR2, SMAD2, ACVR2A | TSHR 792/4885ALDH1A1 1720/4885NOS3 2901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.