Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.33 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | CDC14B | O60729 | 2/20 | 0.32 |
| ▸ | CDC14A | Q9UNH5 | 2/20 | 0.32 |
| ▸ | LPL | P06858 | 1/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.31 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20205524 | 0.93 | GPR84 (0.35) | PGRALOX5LPLLIPGGPR84 | |
| SCHEMBL20205642 | 0.92 | PGR (0.37) | PGRPLA2G2APLA2G4AALOX5CDC14B | |
| SCHEMBL20205309 | 0.92 | PLA2G2A (0.36) | PGRPLA2G2APLA2G4AALOX5CDC14B | |
| SCHEMBL20205313 | 0.92 | CDC14B (0.38) | PGRPLA2G2APLA2G4AALOX5CDC14B | |
| SCHEMBL24649889 | 0.91 | GPR84 (0.35) | PGRALOX5LPLLIPGGPR84 | |
| SCHEMBL20205307 | 0.89 | CDC14B (0.39) | PGRCDC14BCDC14AMAPTALK | |
| SCHEMBL24649753 | 0.89 | PLA2G2A (0.35) | PLA2G2APLA2G4AALOX5CDC14BCDC14A | |
| SCHEMBL20205323 | 0.89 | PLA2G2A (0.34) | PGRPLA2G2APLA2G4AALOX5CDC14B | |
| SCHEMBL20205741 | 0.88 | CDC14B (0.36) | PGRPLA2G2APLA2G4AALOX5CDC14B | |
| SCHEMBL20205319 | 0.88 | CDC14B (0.34) | PGRPLA2G2APLA2G4AALOX5CDC14B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11453680-B2 | Bisbenzofuran-fused indeno[1,2-B]fluorene derivatives and related compounds as materials for organic electroluminescent devices (OLED) | MERCK PATENT GMBH (DE) | 2022-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11453680-B2 | Bisbenzofuran-fused indeno[1,2-B]fluorene derivatives and related compounds as materials for organic electroluminescent devices (OLED) | OCIAD2, OCIAD1, JUND | PGR 4271/4885PLA2G2A 1854/4885PLA2G4A 2777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.