Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | CDC14B | O60729 | 2/20 | 0.32 |
| ▸ | CDC14A | Q9UNH5 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 4/20 | 0.32 |
| ▸ | CA1 | P00915 | 4/20 | 0.32 |
| ▸ | CA2 | P00918 | 4/20 | 0.32 |
| ▸ | CA9 | Q16790 | 4/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 6/20 | 0.32 |
| ▸ | PPARA | Q07869 | 6/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20205376 | 0.96 | ALOX5 (0.36) | ALOX5ENPP3ENPP1CDC14BCDC14A | |
| SCHEMBL20205311 | 0.96 | ALOX5 (0.36) | ALOX5ENPP3ENPP1CDC14BCDC14A | |
| SCHEMBL20205312 | 0.93 | ENPP3 (0.34) | ALOX5ENPP3ENPP1CDC14BCDC14A | |
| SCHEMBL20205324 | 0.91 | CDC14B (0.37) | ALOX5CDC14BCDC14A | |
| SCHEMBL20205315 | 0.91 | CDC14B (0.38) | ALOX5CDC14BCDC14ACA12CA1 | |
| SCHEMBL23351967 | 0.90 | ALOX5 (0.33) | ALOX5 | |
| SCHEMBL20205714 | 0.90 | GPR84 (0.34) | ALOX5CDC14BCDC14ACYP2C9CYP2C19 | |
| SCHEMBL24649901 | 0.88 | ALOX5 (0.36) | ALOX5ENPP3ENPP1CA12CA1 | |
| SCHEMBL20205375 | 0.88 | ENPP3 (0.36) | ALOX5ENPP3ENPP1CDC14BCDC14A | |
| SCHEMBL20205452 | 0.88 | ALOX5 (0.36) | ALOX5CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11453680-B2 | Bisbenzofuran-fused indeno[1,2-B]fluorene derivatives and related compounds as materials for organic electroluminescent devices (OLED) | MERCK PATENT GMBH (DE) | 2022-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11453680-B2 | Bisbenzofuran-fused indeno[1,2-B]fluorene derivatives and related compounds as materials for organic electroluminescent devices (OLED) | OCIAD2, OCIAD1, JUND | ALOX5 354/4885ENPP3 2950/4885ENPP1 2590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.