Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 3/20 | 0.62 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HMGCR | P04035 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24650302 | 0.90 | ADRA1A (0.47) | ADRA1APTGDRPTGDR2LMNAMEN1 | |
| SCHEMBL24650309 | 0.89 | ADRA1A (0.46) | ADRA1APTGDRPTGDR2LMNAAPP | |
| SCHEMBL24650305 | 0.87 | ADRA1A (0.57) | ADRA1AMEN1KMT2ACYP1A2TSHR | |
| SCHEMBL24650909 | 0.87 | ADRA1A (0.64) | ADRA1APTGDR2MEN1KMT2ACYP1A2 | |
| SCHEMBL24651146 | 0.86 | ADRA1A (0.58) | ADRA1ALMNACYP1A2TSHRMAPT | |
| SCHEMBL24650821 | 0.85 | ADRA1A (0.57) | ADRA1AMEN1KMT2ACYP1A2TSHR | |
| SCHEMBL24650380 | 0.82 | ADRA1A (0.43) | ADRA1APTGDRPTGDR2LMNAAPP | |
| SCHEMBL24650914 | 0.82 | ADRA1A (0.46) | ADRA1APTGDRPTGDR2TSHR | |
| SCHEMBL24650490 | 0.82 | ADRA1A (0.62) | ADRA1AMEN1KMT2ACYP1A2MAPT | |
| SCHEMBL24650452 | 0.82 | DRD2 (0.46) | ADRA1ALMNAMEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022238507-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | AWAKN LS EUROPE HOLDINGS LIMITED (IE) | 2022-11-17 | — | — | WO | disclosed |