Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 7/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24650315 | 0.88 | CA12 (0.38) | CA12CA1CA2CA7CA9 | |
| SCHEMBL24650522 | 0.87 | CA1 (0.35) | CA12CA1CA2CA7CA9 | |
| SCHEMBL24650353 | 0.86 | USP2 (0.41) | GAASMN1; SMN2NLRP3USP2KDM4E | |
| SCHEMBL24650363 | 0.86 | NAMPT (0.38) | CA12CA1CA2CA7CA9 | |
| SCHEMBL24650345 | 0.85 | MAPT (0.40) | GAAUSP2ALOX15 | |
| SCHEMBL24650508 | 0.83 | CD69 (0.40) | ALOX15 | |
| SCHEMBL24650478 | 0.82 | POLB (0.39) | GAASMN1; SMN2USP2KDM4EHSD17B10 | |
| SCHEMBL24650336 | 0.81 | CA1 (0.39) | CA12CA1CA2CA7CA9 | |
| SCHEMBL24650882 | 0.80 | CA12 (0.42) | CA12CA1CA2CA7CA9 | |
| SCHEMBL24650429 | 0.79 | DRD2 (0.35) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022238507-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | AWAKN LS EUROPE HOLDINGS LIMITED (IE) | 2022-11-17 | — | — | WO | disclosed |