Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24650457 | 0.87 | NOTUM (0.40) | POLBMAPTALDH1A1ATML3MBTL1 | |
| SCHEMBL24650474 | 0.86 | PYGL (0.38) | — | |
| SCHEMBL24650473 | 0.85 | NAMPT (0.41) | POLBALDH1A1CYP1A2NOTUMSMN1; SMN2 | |
| SCHEMBL24650332 | 0.84 | HSD17B1 (0.40) | — | |
| SCHEMBL24650330 | 0.84 | HSD17B1 (0.36) | — | |
| SCHEMBL24650331 | 0.82 | CA12 (0.40) | USP2GAAKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL24650472 | 0.82 | PYGL (0.44) | MAPTCYP1A2GAATSHRMAPK1 | |
| SCHEMBL24650334 | 0.82 | OPRM1 (0.39) | ALDH1A1GAAKDM4EHSD17B10 | |
| SCHEMBL24650346 | 0.82 | GAA (0.42) | POLBMAPTALDH1A1L3MBTL1CYP1A2 | |
| SCHEMBL20678730 | 0.81 | KDM1A (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022238507-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | AWAKN LS EUROPE HOLDINGS LIMITED (IE) | 2022-11-17 | — | — | WO | disclosed |