Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 3/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24650429 | 0.88 | DRD2 (0.35) | CA1CA2CA12CA7CA9 | |
| SCHEMBL24650331 | 0.87 | CA12 (0.40) | CA1CA2CA12CA7CA9 | |
| SCHEMBL24651045 | 0.86 | MAPT (0.34) | CA1CA2CA12CA7CA9 | |
| SCHEMBL24650526 | 0.86 | MTNR1A (0.40) | HTR1ADRD2DRD3MTNR1AMTNR1B | |
| SCHEMBL24650508 | 0.85 | CD69 (0.40) | HTR1ADRD2DRD3MAOAMAOB | |
| SCHEMBL24650505 | 0.84 | GLA (0.38) | ACHEALDH1A1GAAMTNR1AMTNR1B | |
| SCHEMBL24650474 | 0.81 | PYGL (0.38) | MTNR1AMTNR1B | |
| SCHEMBL24650342 | 0.81 | CA1 (0.34) | CA1CA2CA12CA7CA9 | |
| SCHEMBL24650315 | 0.80 | CA12 (0.38) | CA1CA2CA12CA7CA9 | |
| SCHEMBL24650350 | 0.80 | DRD2 (0.36) | DRD2DRD3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022238507-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | AWAKN LS EUROPE HOLDINGS LIMITED (IE) | 2022-11-17 | — | — | WO | disclosed |