Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.36 |
| ▸ | KYAT3 | Q6YP21 | 1/20 | 0.36 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24650376 | 0.84 | TSHR (0.34) | ADRA1AMAPTALDH1A1HSD17B10 | |
| SCHEMBL24650374 | 0.78 | MAPK1 (0.42) | TDP1MAPTALDH1A1DRD2DRD3 | |
| SCHEMBL24651008 | 0.76 | ADRA1A (0.44) | ADRA1ATDP1ALDH1A1DRD2DRD3 | |
| SCHEMBL24650803 | 0.76 | ADRA1A (0.54) | ADRA1ATDP1DRD2DRD3AADAT | |
| SCHEMBL8542873 | 0.76 | ADRA1A (0.63) | ADRA1ADRD2DRD3POLB | |
| SCHEMBL24650542 | 0.75 | DRD3 (0.37) | ADRA1ADRD2DRD3POLB | |
| SCHEMBL24650805 | 0.75 | ADRA1A (0.68) | ADRA1ATDP1MAPTALDH1A1DRD2 | |
| SCHEMBL833488 | 0.74 | TDP1 (0.45) | TDP1MAPTALDH1A1POLBHSD17B10 | |
| Hydrochloric Acid SCHEMBL9696131 | 0.74 | ADRA1A (0.61) | ADRA1ADRD2DRD3POLB | |
| SCHEMBL24650804 | 0.73 | DRD2 (0.41) | ADRA1AALDH1A1DRD2DRD3KYAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022238507-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | AWAKN LS EUROPE HOLDINGS LIMITED (IE) | 2022-11-17 | — | — | WO | disclosed |