Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24650745 | 0.94 | PPARD (0.40) | HPGDCA1CA2ACHEADRA1A | |
| SCHEMBL24651156 | 0.91 | LMNA (0.43) | LMNAMCL1HPGDCA1CA2 | |
| SCHEMBL24650394 | 0.90 | MCL1 (0.42) | LMNAMCL1ACHEL3MBTL1PPARD | |
| SCHEMBL24650731 | 0.89 | HPGD (0.40) | HPGDCA1CA2ACHEADRA1A | |
| SCHEMBL24650378 | 0.87 | CA1 (0.42) | LMNAMCL1HPGDCA1CA2 | |
| SCHEMBL24650407 | 0.85 | CA1 (0.40) | HPGDCA1CA2ACHEADRA1A | |
| SCHEMBL24650259 | 0.85 | FFAR1 (0.41) | LMNACA1CA2ACHEPPARD | |
| SCHEMBL24650728 | 0.84 | FFAR4 (0.40) | MCL1ACHEPPARDFFAR1PPARG | |
| SCHEMBL24650258 | 0.81 | FFAR4 (0.40) | ACHEPPARDFFAR1TSHRKMT2A | |
| SCHEMBL24650391 | 0.81 | CA1 (0.42) | LMNAHPGDCA1CA2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022238507-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | AWAKN LS EUROPE HOLDINGS LIMITED (IE) | 2022-11-17 | — | — | WO | disclosed |