Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | PTPRB | P23467 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CD69 | Q07108 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24650379 | 0.90 | L3MBTL1 (0.43) | LMNAPOLBHSD17B10ALOX15TSHR | |
| SCHEMBL24650391 | 0.88 | CA1 (0.42) | CA1CA2ACHELMNAADRA1A | |
| SCHEMBL24650401 | 0.87 | LMNA (0.43) | CA1CA2ACHELMNAADRA1A | |
| SCHEMBL24650745 | 0.86 | PPARD (0.40) | CA1CA2ACHEADRA1ATSHR | |
| SCHEMBL24650404 | 0.85 | MEN1 (0.43) | CA1CA2ACHELMNAPOLB | |
| SCHEMBL24650731 | 0.81 | HPGD (0.40) | CA1CA2ACHEADRA1AHPGD | |
| SCHEMBL24651156 | 0.81 | LMNA (0.43) | CA1CA2ACHELMNAADRA1A | |
| SCHEMBL24650407 | 0.80 | CA1 (0.40) | CA1CA2ACHEADRA1AHPGD | |
| SCHEMBL24650997 | 0.79 | POLB (0.49) | CA1CA2LMNAPOLBSMN1; SMN2 | |
| SCHEMBL24650913 | 0.79 | ACHE (0.42) | CA1CA2ACHELMNAADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022238507-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | AWAKN LS EUROPE HOLDINGS LIMITED (IE) | 2022-11-17 | — | — | WO | disclosed |