Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 5/20 | 0.47 |
| ▸ | CA2 | P00918 | 5/20 | 0.47 |
| ▸ | CA12 | O43570 | 4/20 | 0.47 |
| ▸ | CA7 | P43166 | 4/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4637133 | 1.00 | KDM4E (0.47) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL10247342 | 0.88 | DRD2 (0.57) | MAPTALDH1A1HSD17B10 | |
| SCHEMBL355227 | 0.88 | DRD2 (0.57) | MAPTALDH1A1HSD17B10 | |
| SCHEMBL10247424 | 0.88 | DRD2 (0.57) | MAPTALDH1A1HSD17B10 | |
| SCHEMBL353908 | 0.88 | OPRK1 (0.54) | — | |
| Hydrochloric Acid SCHEMBL353594 | 0.86 | DRD2 (0.56) | MAPTALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL354608 | 0.86 | DRD2 (0.56) | MAPTALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL353391 | 0.86 | OPRK1 (0.53) | — | |
| Hydrochloric Acid SCHEMBL354592 | 0.86 | DRD2 (0.56) | MAPTALDH1A1HSD17B10 | |
| SCHEMBL16716449 | 0.85 | CHRNB2 (0.51) | KDM4EMAPTALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022238507-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | AWAKN LS EUROPE HOLDINGS LIMITED (IE) | 2022-11-17 | — | — | WO | disclosed |