Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.40 |
| ▸ | NQO2 | P16083 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24651052 | 0.93 | BRD4 (0.41) | HTTMTNR1AMTNR1BNQO2L3MBTL1 | |
| SCHEMBL24650326 | 0.92 | BRD4 (0.44) | MTNR1AMTNR1BNQO2L3MBTL1PPARD | |
| SCHEMBL24650433 | 0.91 | PPARD (0.41) | HTTMTNR1AMTNR1BNQO2L3MBTL1 | |
| SCHEMBL24650426 | 0.90 | PPARD (0.42) | HTTMTNR1AMTNR1BNQO2L3MBTL1 | |
| SCHEMBL24650515 | 0.90 | NQO2 (0.41) | HTTMTNR1AMTNR1BNQO2L3MBTL1 | |
| SCHEMBL24650431 | 0.90 | MTNR1A (0.42) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL24650360 | 0.86 | BRD4 (0.50) | L3MBTL1PPARDBRD4 | |
| SCHEMBL24651040 | 0.85 | FFAR4 (0.45) | MTNR1AMTNR1BNQO2L3MBTL1PPARD | |
| SCHEMBL24651046 | 0.84 | PPARD (0.42) | HTTL3MBTL1PPARDBRD4MAPT | |
| SCHEMBL24650321 | 0.84 | BRD4 (0.40) | MTNR1AMTNR1BNQO2BRD4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022238507-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | AWAKN LS EUROPE HOLDINGS LIMITED (IE) | 2022-11-17 | — | — | WO | disclosed |