Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24650356 | 0.93 | BRD4 (0.46) | BRD4ALDH1A1GAAHPGDNPC1 | |
| SCHEMBL24650326 | 0.92 | BRD4 (0.44) | BRD4GAATSHRMTNR1AMTNR1B | |
| SCHEMBL24650323 | 0.91 | ALDH1A1 (0.40) | BRD4ALDH1A1GAAHPGDNPC1 | |
| SCHEMBL24650334 | 0.90 | OPRM1 (0.39) | ALDH1A1GAAHPGDMTNR1AMTNR1B | |
| SCHEMBL24650431 | 0.90 | MTNR1A (0.42) | MTNR1AMTNR1BDRD2DRD3NQO2 | |
| SCHEMBL24650325 | 0.87 | BRD4 (0.36) | BRD4ALDH1A1GAAHPGDKDM4E | |
| SCHEMBL24650434 | 0.86 | DRD2 (0.41) | ALDH1A1HPGDMTNR1AMTNR1BHSD17B10 | |
| SCHEMBL24650360 | 0.86 | BRD4 (0.50) | BRD4 | |
| SCHEMBL24650435 | 0.84 | HTT (0.41) | BRD4ALDH1A1MTNR1AMTNR1BHSD17B10 | |
| SCHEMBL24650457 | 0.83 | NOTUM (0.40) | ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022238507-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | AWAKN LS EUROPE HOLDINGS LIMITED (IE) | 2022-11-17 | — | — | WO | disclosed |