Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | DRD3 | P35462 | 3/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24650449 | 0.80 | LMNA (0.47) | DRD2DRD3S1PR5SLC18A3LMNA | |
| SCHEMBL24650453 | 0.79 | DRD2 (0.46) | DRD2DRD3HTR1AHTR1DHTR1B | |
| SCHEMBL24650450 | 0.77 | DRD2 (0.47) | DRD2DRD3S1PR5SLC18A3LMNA | |
| SCHEMBL24650456 | 0.77 | PDE4A (0.42) | DRD2DRD3HTR1AHTR1DHTR1B | |
| SCHEMBL24650454 | 0.77 | PTGIR (0.49) | POLB | |
| SCHEMBL24650455 | 0.75 | DRD2 (0.42) | DRD2DRD3HTR1AHTR1DHTR1B | |
| SCHEMBL24650452 | 0.73 | DRD2 (0.46) | DRD2DRD3LMNAADRB2ADRB1 | |
| SCHEMBL385443 | 0.73 | DRD2 (0.73) | DRD2DRD3HTR1AADRA1A | |
| SCHEMBL31324598 | 0.73 | DRD2 (0.73) | DRD2DRD3HTR1AADRA1A | |
| SCHEMBL24650447 | 0.71 | USP2 (0.45) | DRD2DRD3LMNAPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022238507-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | AWAKN LS EUROPE HOLDINGS LIMITED (IE) | 2022-11-17 | — | — | WO | disclosed |