Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | S1PR5 | Q9H228 | 9/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | PTGIR | P43119 | 1/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24650454 | 0.86 | PTGIR (0.49) | PTGIR | |
| SCHEMBL24650450 | 0.85 | DRD2 (0.47) | LMNAS1PR5DRD2DRD3SLC18A3 | |
| SCHEMBL24650455 | 0.83 | DRD2 (0.42) | S1PR5DRD2DRD3SLC18A3 | |
| SCHEMBL24650403 | 0.82 | LMNA (0.39) | LMNAS1PR5DRD2DRD3 | |
| SCHEMBL24650453 | 0.82 | DRD2 (0.46) | S1PR5DRD2DRD3SLC18A3 | |
| SCHEMBL24651147 | 0.81 | PTGDR2 (0.40) | LMNADRD2DRD3RXRARXRB | |
| SCHEMBL24650451 | 0.80 | DRD2 (0.46) | LMNAS1PR5DRD2DRD3SLC18A3 | |
| SCHEMBL24650456 | 0.80 | PDE4A (0.42) | LMNAS1PR5DRD2DRD3 | |
| SCHEMBL24650390 | 0.79 | LMNA (0.46) | LMNADRD2DRD3 | |
| SCHEMBL24651157 | 0.79 | LMNA (0.41) | LMNAS1PR5DRD2DRD3RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022238507-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | AWAKN LS EUROPE HOLDINGS LIMITED (IE) | 2022-11-17 | — | — | WO | disclosed |