Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.34 |
| ▸ | FABP3 | P05413 | 3/20 | 0.34 |
| ▸ | FABP4 | P15090 | 3/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24650406 | 0.93 | FYN (0.49) | FYNMAPTKDM4ETSHRHSD17B10 | |
| SCHEMBL24650755 | 0.85 | MAPT (0.45) | FYNMAPTKDM4ETSHRHSD17B10 | |
| SCHEMBL24650743 | 0.84 | TSHR (0.44) | MAPTTSHRALDH1A1PTGDR2FFAR4 | |
| SCHEMBL24650737 | 0.84 | TSHR (0.44) | KDM4ETSHRHSD17B10ALDH1A1PTGDR2 | |
| SCHEMBL24650995 | 0.84 | FYN (0.52) | FYNMAPTKDM4ETSHRHSD17B10 | |
| SCHEMBL24650417 | 0.83 | PDE4A (0.43) | FYNMAPTKDM4EHSD17B10NFKB1 | |
| SCHEMBL24650248 | 0.81 | PTGDR2 (0.41) | FYNMAPTKDM4ETSHRHSD17B10 | |
| SCHEMBL24650742 | 0.79 | FYN (0.42) | FYNMAPTKDM4ETSHRHSD17B10 | |
| SCHEMBL24650550 | 0.78 | FYN (0.52) | FYNMAPTKDM4EHSD17B10NFKB1 | |
| SCHEMBL24650385 | 0.77 | LMNA (0.51) | MAPTHSD17B10ALDH1A1PTGDR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022238507-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | AWAKN LS EUROPE HOLDINGS LIMITED (IE) | 2022-11-17 | — | — | WO | disclosed |