Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24650743 | 0.93 | TSHR (0.44) | LMNAALDH1A1PPARAPDE4BPDE4D | |
| SCHEMBL24650399 | 0.89 | ACHE (0.41) | LMNAKMT2ACYP3A4PTGDR2HSD17B10 | |
| SCHEMBL24650749 | 0.87 | KMT2A (0.41) | LMNAALDH1A1PDE4BCA1CA2 | |
| SCHEMBL24650997 | 0.85 | POLB (0.49) | LMNAALDH1A1CA1CA2KMT2A | |
| SCHEMBL24650406 | 0.84 | FYN (0.49) | LMNAALDH1A1CA1CA2MAPT | |
| SCHEMBL24650744 | 0.84 | PDE4B (0.47) | ALDH1A1PDE4BKMT2APDE4DCYP3A4 | |
| SCHEMBL24650754 | 0.83 | MAPT (0.46) | ALDH1A1PDE4BCA1CA2KMT2A | |
| SCHEMBL24650737 | 0.82 | TSHR (0.44) | ALDH1A1KMT2ACYP3A4PTGDR2HSD17B10 | |
| SCHEMBL24651156 | 0.81 | LMNA (0.43) | LMNAPPARACA1CA2PTGDR2 | |
| SCHEMBL24650410 | 0.80 | PDE4B (0.53) | ALDH1A1PDE4BKMT2APDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022238507-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | AWAKN LS EUROPE HOLDINGS LIMITED (IE) | 2022-11-17 | — | — | WO | disclosed |