Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24650749 | 0.93 | KMT2A (0.41) | MAPTPDE4BPDE4DGAAKMT2A | |
| SCHEMBL24650756 | 0.91 | MAPT (0.45) | MAPTPDE4BPDE4DPDE4APDE4C | |
| SCHEMBL24650410 | 0.88 | PDE4B (0.53) | PDE4BPDE4DPDE4APDE4CKMT2A | |
| SCHEMBL24650755 | 0.88 | MAPT (0.45) | MAPTPDE4BPDE4DPDE4APDE4C | |
| SCHEMBL24650743 | 0.88 | TSHR (0.44) | MAPTPDE4BPDE4DHPGDHTT | |
| SCHEMBL24650389 | 0.85 | HMGCR (0.50) | GAAKMT2ACA1CA2ACHE | |
| SCHEMBL24650750 | 0.84 | ACHE (0.40) | MAPTPDE4BPDE4DPDE4APDE4C | |
| SCHEMBL24650385 | 0.83 | LMNA (0.51) | MAPTPDE4BPDE4DKMT2ACA1 | |
| SCHEMBL24650814 | 0.82 | MAPT (0.42) | MAPTPDE4BPDE4DPDE4APDE4C | |
| SCHEMBL24650948 | 0.82 | SLC2A1 (0.41) | GAAKMT2ACA1CA2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022238507-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | AWAKN LS EUROPE HOLDINGS LIMITED (IE) | 2022-11-17 | — | — | WO | disclosed |