Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | RORC | P51449 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32667078 | 0.79 | L3MBTL1 (0.50) | PTK2L3MBTL1GAACYP1A2PIK3C3 | |
| SCHEMBL7029088 | 0.78 | PTK2 (0.54) | PTK2L3MBTL1GAAJAK2JAK1 | |
| SCHEMBL23841368 | 0.78 | NNMT (0.45) | TYK2CNR2CYP1A2TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL32667080 | 0.77 | L3MBTL1 (0.49) | PTK2L3MBTL1GAACYP1A2PIK3C3 | |
| SCHEMBL20031484 | 0.77 | PTK2 (0.53) | PTK2L3MBTL1GAAJAK2JAK1 | |
| SCHEMBL23610778 | 0.77 | PTK2 (0.53) | PTK2L3MBTL1GAAJAK2JAK1 | |
| SCHEMBL25118045 | 0.75 | PTK2 (0.51) | PTK2L3MBTL1GAAJAK2JAK1 | |
| SCHEMBL5318470 | 0.75 | PTK2 (0.51) | PTK2L3MBTL1GAAJAK2JAK1 | |
| SCHEMBL31493083 | 0.75 | PTK2 (0.54) | PTK2L3MBTL1GAAJAK2JAK1 | |
| SCHEMBL17606874 | 0.75 | PTK2 (0.54) | PTK2L3MBTL1GAAJAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11466013-B2 | ERK inhibitor and use thereof | BETTA PHARMACEUTICALS CO., LTD (CN) | 2022-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11466013-B2 | ERK inhibitor and use thereof | MAPK1, MAPK4, MAPK7 | PTK2 48/4885L3MBTL1 2934/4885GAA 2202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.