Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | PDCD1LG2 | Q9BQ51 | 2/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.31 |
| ▸ | ALPL | P05186 | 1/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2470370 | 0.91 | MAP4K1 (0.36) | MAP4K1KMOGRM5ALOX5APFEN1 | |
| SCHEMBL2465186 | 0.89 | MAP4K1 (0.32) | MAP4K1ALOX5APFEN1PDCD1LG2CD274 | |
| SCHEMBL2466406 | 0.88 | FFAR4 (0.32) | ALOX5APFEN1FFAR4 | |
| SCHEMBL2467541 | 0.86 | ALDH1A1 (0.37) | ALOX5APFEN1PDCD1LG2CD274FFAR4 | |
| SCHEMBL2465231 | 0.85 | KMO (0.41) | MAP4K1KMOGRM5ALOX5APFEN1 | |
| SCHEMBL2465298 | 0.84 | ALOX5AP (0.37) | ALOX5APFEN1PDCD1LG2CD274ALPL | |
| SCHEMBL3454208 | 0.84 | ALOX5AP (0.37) | ALOX5APFEN1PDCD1LG2CD274ALPL | |
| SCHEMBL2469850 | 0.84 | PPARA (0.33) | KMOFFAR4 | |
| SCHEMBL2463884 | 0.82 | ALOX5AP (0.38) | ALOX5APFEN1FFAR4 | |
| SCHEMBL3332442 | 0.82 | MAP4K1 (0.39) | MAP4K1KMOGRM5ALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2060566-B1 | Poly-substituted aryls | DOW AGROSCIENCES LLC (US) | 2016-06-08 | — | — | EP | claimed |
| EP-2939540-A1 | HERBICIDE SAFENER COMBINATION | Bayer Intellectual Property GmbH (DE) | 2015-11-04 | — | — | EP | disclosed |
| EP-2939541-A1 | HERBICIDE SAFENER COMBINATION | Bayer Intellectual Property GmbH (DE) | 2015-11-04 | — | — | EP | disclosed |
| EP-2369929-A2 | HERBICIDE-SAFENER COMBINATION | Bayer CropScience AG (DE) | 2011-10-05 | — | — | EP | disclosed |
| WO-2010060581-A2 | HERBICIDE-SAFENER COMBINATION | BAYER CROPSCIENCE AG (DE) | 2010-06-03 | — | — | WO | disclosed |
| EP-2191719-A1 | Herbicide safener combination | Bayer CropScience AG (DE) | 2010-06-02 | — | — | EP | disclosed |