Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR1E | P28566 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20915560 | 0.80 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2ALPLNPC1RAB9A | |
| SCHEMBL2387037 | 0.79 | AKT2 (0.44) | PTGS2ALDH1A1SMN1; SMN2ALPLMAPK14 | |
| SCHEMBL20915705 | 0.73 | XDH (0.49) | PTGS2ALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL14307558 | 0.72 | MAPK14 (0.40) | PTGS2MAPK14NPC1RAB9AAXL | |
| SCHEMBL25210468 | 0.72 | ALDH1A1 (0.47) | HTR1AHTR1DHTR2AHTR2CHTR1E | |
| SCHEMBL23294286 | 0.72 | MAP2K4 (0.38) | ALPLMAPK1RAB9A | |
| SCHEMBL17969086 | 0.72 | ERBB2 (0.49) | HTR1AHTR1DHTR2AHTR2CHTR1E | |
| SCHEMBL25220966 | 0.71 | MAPK14 (0.57) | ALDH1A1MAPK14MAPK1KDM4ETSHR | |
| SCHEMBL14705874 | 0.71 | HAO1 (0.49) | ALDH1A1SMN1; SMN2ALPLMAPK14MAPK1 | |
| SCHEMBL18006079 | 0.71 | ERBB2 (0.47) | ALDH1A1SMN1; SMN2ADORA2AADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022234271-A1 | HETEROARYL COMPOUNDS USEFUL IN THE TREATMENT OF COGNITIVE DISORDERS | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2022-11-10 | — | — | WO | disclosed |