Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALPL | P05186 | 1/20 | 0.30 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24656118 | 0.81 | KDM4E (0.41) | KDM4ECYP1A2PDE10APDGFRBPDGFRA | |
| SCHEMBL18869541 | 0.68 | PDE10A (0.46) | KDM4EPDE10AKMT2ASMN1; SMN2RAB9A | |
| SCHEMBL12338408 | 0.66 | KDM4E (0.50) | KDM4ECYP1A2PDE10ATLR8RAB9A | |
| SCHEMBL3063625 | 0.66 | KDM4E (0.50) | KDM4ECYP1A2PDE10ATLR8RAB9A | |
| SCHEMBL20093302 | 0.65 | SMN1; SMN2 (0.34) | KDM4EPDE10AKMT2ASMN1; SMN2RAB9A | |
| SCHEMBL820776 | 0.64 | PDE10A (0.47) | KDM4ECYP1A2PDE10APDGFRBPDGFRA | |
| SCHEMBL24590442 | 0.63 | PDE10A (0.43) | KDM4ECYP1A2PDE10AKMT2ASMN1; SMN2 | |
| SCHEMBL5720367 | 0.62 | PDE10A (0.48) | KDM4EPDE10APDGFRBPDGFRAKMT2A | |
| SCHEMBL18661272 | 0.62 | PDE10A (0.44) | KDM4ECYP1A2PDE10APDGFRBPDGFRA | |
| SCHEMBL11597014 | 0.61 | CYP1A2 (0.52) | KDM4ECYP1A2TLR8PDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220332713-A1 | Monoacylglycerol Lipase Modulators | JANSSEN PHARMACEUTICA NV (BE) | 2022-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220332713-A1 | Monoacylglycerol Lipase Modulators | MGLL, LPL, PNLIP | KDM4E 2437/4885CYP1A2 540/4885MMP2 2082/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.