Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 5/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23479987 | 0.80 | SIGMAR1 (0.42) | POLBGFERALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL29851330 | 0.80 | SIGMAR1 (0.42) | POLBGFERALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL23480485 | 0.77 | HSD11B1 (0.38) | GFERALDH1A1SIGMAR1 | |
| SCHEMBL29171007 | 0.77 | HSD11B1 (0.38) | GFERALDH1A1SIGMAR1 | |
| SCHEMBL23480099 | 0.77 | HSD11B1 (0.38) | GFERALDH1A1SIGMAR1 | |
| SCHEMBL24658852 | 0.73 | ALDH1A1 (0.34) | GAAPOLBGFERALDH1A1SMN1; SMN2 | |
| SCHEMBL12749148 | 0.72 | POLB (0.51) | POLBALDH1A1 | |
| SCHEMBL29973250 | 0.72 | POLB (0.51) | POLBALDH1A1 | |
| SCHEMBL14180558 | 0.67 | KDM4E (0.58) | GAAPOLBALDH1A1NPSR1HTT | |
| SCHEMBL14180548 | 0.65 | NSD2 (0.58) | POLBMEN1KMT2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4074697-A2 | NOVEL ADAMANTANE DERIVATIVES AS INHIBITORS OF FOCAL ADHESION KINASE | Samjin Pharmaceutical Co., Ltd. (KR) | 2022-10-19 | — | — | EP | disclosed |