SCHEMBL24660367

SCHEMBL24660367

NC(=O)c1ccc(NNC(=O)OCC2c3ccccc3-c3ccccc32)nc1

nearest known ligand 0.54

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.54
EPHX2 P34913 1/20 0.46
NNMT P40261 1/20 0.42
POLB P06746 1/20 0.39
GAA P10253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL346077 0.90 KMT2A (0.52) KMT2AEPHX2POLBGAA
SCHEMBL10015137 0.87 KMT2A (0.49) KMT2AEPHX2POLBGAA
SCHEMBL3562349 0.82 KMT2A (0.44) KMT2AEPHX2POLBGAA
SCHEMBL13349297 0.81 KMT2A (0.50) KMT2AEPHX2POLB
SCHEMBL7872045 0.78 HCAR3 (0.51) KMT2AEPHX2
SCHEMBL31370084 0.75 MDM4 (0.51) KMT2A
SCHEMBL12235815 0.74 KMT2A (0.64) KMT2AEPHX2GAA
SCHEMBL178731 0.74 KMT2A (0.57) KMT2AEPHX2GAA
SCHEMBL15948331 0.73 KMT2A (0.53) KMT2AEPHX2
SCHEMBL28552605 0.72 EPHX2 (0.52) KMT2AEPHX2POLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022178592-A1 SOLID PHASE SYNTHESIS OF GLUTAMATE-UREA-LYSINE DERIVED (GUL DERIVED) PROSTATE-SPECIFIC MEMBRANE ANTIGEN (PSMA) TARGETING CONJUGATES AND THEIR USE AS PRECURSORS FOR THERAPEUTIC AND / OR DIAGNOSTIC AGENTS Telix International Pty Ltd (AU) 2022-09-01 WO disclosed