Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 8/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GCK | P35557 | 3/20 | 0.46 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | RARG | P13631 | 1/20 | 0.42 |
| ▸ | FABP7 | O15540 | 1/20 | 0.42 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.42 |
| ▸ | MDM4 | O15151 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL346077 | 0.88 | KMT2A (0.52) | HCAR3EPHX2KMT2AGCKRARA | |
| SCHEMBL28552605 | 0.84 | EPHX2 (0.52) | EPHX2KMT2ATP53 | |
| SCHEMBL6937376 | 0.84 | EPHX2 (0.49) | EPHX2KMT2AFABP7FABP5MDM4 | |
| SCHEMBL29679239 | 0.81 | KMT2A (0.51) | EPHX2KMT2AFABP7FABP5MDM4 | |
| SCHEMBL29401210 | 0.81 | EPHX2 (0.63) | EPHX2KMT2AFABP7FABP5MDM4 | |
| SCHEMBL21303577 | 0.81 | EPHX2 (0.56) | EPHX2KMT2AFABP7FABP5 | |
| SCHEMBL118052 | 0.81 | EPHX2 (0.63) | EPHX2KMT2AFABP7FABP5MDM4 | |
| SCHEMBL29561956 | 0.81 | EPHX2 (0.63) | EPHX2KMT2AFABP7FABP5MDM4 | |
| SCHEMBL24660367 | 0.78 | KMT2A (0.54) | EPHX2KMT2A | |
| SCHEMBL7913189 | 0.78 | EPHX2 (0.59) | EPHX2KMT2AFABP7FABP5MDM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102167728-B | Improved gastrin releasing peptide compounds | BRACCO IMAGING SPA | 2013-05-29 | — | — | CN | disclosed |
| CN-102167728-A | Improved gastrin releasing peptide compounds | BRACCO IMAGING SPA | 2011-08-31 | — | — | CN | disclosed |
| CN-1897980-A | Improved gastrin releasing peptide compounds | BRACCO IMAGING SPA (IT) | 2007-01-17 | — | — | CN | disclosed |
| CN-1738650-A | Improved gastrin releasing peptide compounds | BRACCO IMAGING SPA (IT) | 2006-02-22 | — | — | CN | disclosed |
| US-6326403-B1 | CARDIOVASCULAR DISORDERS | MERCK PATENT GESELLSCHAFT MIT (DE) | 2001-12-04 | — | — | US | disclosed |
| CN-1309633-A | Diacylhydrazine derivatives as integrin inhibitors | MERCK PATENT GMBH (DE) | 2001-08-22 | — | — | CN | disclosed |