Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | USP2 | O75604 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19387118 | 0.88 | HTT (0.80) | HTTTSHRUSP2HSD17B10ALDH1A1 | |
| SCHEMBL22279732 | 0.88 | HTT (0.80) | HTTTSHRUSP2HSD17B10ALDH1A1 | |
| SCHEMBL15967718 | 0.88 | HTT (0.80) | HTTTSHRUSP2HSD17B10ALDH1A1 | |
| SCHEMBL15289758 | 0.88 | HTT (0.80) | HTTTSHRUSP2HSD17B10ALDH1A1 | |
| SCHEMBL10731583 | 0.88 | HTT (0.80) | HTTTSHRUSP2HSD17B10ALDH1A1 | |
| SCHEMBL20022939 | 0.80 | ALDH1A1 (0.56) | HTTTSHRUSP2HSD17B10ALDH1A1 | |
| SCHEMBL20022945 | 0.80 | ALDH1A1 (0.56) | HTTTSHRUSP2HSD17B10ALDH1A1 | |
| SCHEMBL15958848 | 0.78 | HTT (1.00) | HTTTSHRUSP2HSD17B10ALDH1A1 | |
| SCHEMBL597717 | 0.78 | HTT (1.00) | HTTTSHRUSP2HSD17B10ALDH1A1 | |
| SCHEMBL10731869 | 0.77 | HTT (0.68) | HTTTSHRUSP2HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022216628-A1 | CYCLIC RUTHENIUM BENZYLIDENE INITIATORS FOR ENHANCED RING‑EXPANSION METATHESIS POLYMERIZATION | UNIVERSITY OF WASHINGTON (US) | 2022-10-13 | — | — | WO | disclosed |