Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20022939 | 0.83 | ALDH1A1 (0.56) | ALDH1A1KMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL24663166 | 0.80 | HTT (0.64) | ALDH1A1KMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL14344292 | 0.75 | ALDH1A1 (0.84) | ALDH1A1KMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL10022041 | 0.75 | ALDH1A1 (0.70) | ALDH1A1KMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL13528565 | 0.75 | ALDH1A1 (0.84) | ALDH1A1KMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL19708133 | 0.73 | ALDH1A1 (0.52) | ALDH1A1KMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL19020482 | 0.73 | ALDH1A1 (0.52) | ALDH1A1KMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL14727215 | 0.73 | ALDH1A1 (0.52) | ALDH1A1KMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL17470589 | 0.72 | ALDH1A1 (0.66) | ALDH1A1KMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL21729686 | 0.72 | ALDH1A1 (0.66) | ALDH1A1KMT2AMEN1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180094099-A1 | BOTTLEBRUSH COPOLYMERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180094099-A1 | BOTTLEBRUSH COPOLYMERS AND USES THEREOF | TRIB1, TRIB2, ABCB11 | ALDH1A1 1610/4885KMT2A 4854/4885MEN1 4342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.