SCHEMBL2466431

SCHEMBL2466431

CC(CC(=O)O)c1ccc(Cl)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 3/20 0.61
GABBR2 O75899 3/20 0.58
GABBR1 Q9UBS5 3/20 0.58
CYP2C9 P11712 3/20 0.58
KMT2A Q03164 3/20 0.58
LMNA P02545 2/20 0.58
CYP2D6 P10635 2/20 0.58
CYP2C19 P33261 2/20 0.58
MEN1 O00255 2/20 0.58
CYP3A4 P08684 1/20 0.58
ADORA3 P0DMS8 1/20 0.58
NFKB1 P19838 1/20 0.58
DRD3 P35462 1/20 0.58
BLM P54132 1/20 0.58
CYP1A2 P05177 1/20 0.58
THRB P10828 1/20 0.58
TSHR P16473 1/20 0.58
HSD17B10 Q99714 1/20 0.53
POLB P06746 2/20 0.50
ACHE P22303 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2556175 1.00 FFAR1 (0.61) FFAR1GABBR2GABBR1CYP2C9KMT2A
SCHEMBL2554154 1.00 FFAR1 (0.61) FFAR1GABBR2GABBR1CYP2C9KMT2A
SCHEMBL11332403 0.88 FFAR1 (0.62) FFAR1GABBR2GABBR1CYP2C9KMT2A
SCHEMBL1225215 0.82 GABBR2 (0.47) FFAR1GABBR2GABBR1CYP2C9KMT2A
SCHEMBL25152959 0.82 ACHE (0.67) FFAR1KMT2ACYP2C19TSHRPOLB
SCHEMBL12883165 0.82 ACHE (0.67) FFAR1KMT2ACYP2C19TSHRPOLB
SCHEMBL7559049 0.82 ACHE (0.67) FFAR1KMT2ACYP2C19TSHRPOLB
SCHEMBL13140496 0.82 FFAR1 (0.61) FFAR1CYP2C9LMNACYP2D6CYP2C19
SCHEMBL31522488 0.82 FFAR1 (0.61) FFAR1CYP2C9LMNACYP2D6CYP2C19
SCHEMBL1162528 0.82 FFAR1 (0.61) FFAR1CYP2C9LMNACYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12502367-B2 Oral baclofen solutions Metacel Pharmaceuticals, LLC (US) 2025-12-23 US claimed
US-20220233483-A1 ORAL BACLOFEN SOLUTIONS ROSEMONT PHARMACEUTICALS LLC 2022-07-28 US claimed
EP-2922812-B1 PROCESS FOR PREPARING A SALT OF A SULFURIZED ALKYL-SUBSTITUTED HYDROXYAROMATIC COMPOSITION CHEVRON ORONITE CO (US) 2021-08-11 EP claimed
EP-2922812-A1 PROCESS FOR PREPARING A SALT OF A SULFURIZED ALKYL-SUBSTITUTED HYDROXYAROMATIC COMPOSITION Chevron Oronite Company LLC (US) 2015-09-30 EP claimed
US-8772209-B2 Process for preparing a salt of a sulfurized alkyl-substituted hydroxyaromatic composition CHEVRON ORONITE COMPANY LLS (US) 2014-07-08 US claimed
WO-2014081538-A1 PROCESS FOR PREPARING A SALT OF A SULFURIZED ALKYL-SUBSTITUTED HYDROXYAROMATIC COMPOSITION CHEVRON ORONITE COMPANY LLC (US) 2014-05-30 WO claimed
US-20140142347-A1 PROCESS FOR PREPARING A SALT OF A SULFURIZED ALKYL-SUBSTITUTED HYDROXYAROMATIC COMPOSITION CHEVRON ORONITE COMPANY LLC (US) 2014-05-22 US claimed
CN-102341099-A Sustained release oral dosage forms of an R-baclofen prodrug XENOPORT INC 2012-02-01 CN claimed
EP-2010508-A1 THIAZOL-GUANIDINE DERIVATIVES USEFUL AS A (BETA)- RELATED PATHOLOGIES AstraZeneca AB (SE) 2009-01-07 EP claimed
WO-2007120096-A1 THIAZOL-GUANIDINE DERIVATIVES USEFUL AS A (BETA)- RELATED PATHOLOGIES ASTRAZENECA AB (SE) 2007-10-25 WO claimed
EP-1786872-A1 POWDER COATING COMPOSITIONS PPG Industries Ohio, Inc. (US) 2007-05-23 EP claimed
US-7132477-B2 Powder coating compositions PPG INDUSTRIES OHIO, INC. (US) 2006-11-07 US claimed
WO-2006026492-A1 POWDER COATING COMPOSITIONS PPG INDUSTRIES OHIO, INC. (US) 2006-03-09 WO claimed
US-20050025987-A1 Powder coating compositions PPG INDUSTRIES OHIO INC. 2005-02-03 US claimed
US-12502367-B2 Oral baclofen solutions Metacel Pharmaceuticals, LLC (US) 2025-12-23 US disclosed
US-12502367-B2 Oral baclofen solutions Metacel Pharmaceuticals, LLC (US) 2025-12-23 US disclosed
EP-2922934-B1 SOLVENT EXTRACTION FOR PREPARING A SALT OF A SULFURIZED ALKYL-SUBSTITUTED HYDROXYAROMATIC COMPOSITION CHEVRON ORONITE CO (US) 2022-12-14 EP disclosed
EP-0968206-A1 N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS BERLEX LABORATORIES, INC. (US) 2000-01-05 EP disclosed
WO-1998037079-A1 N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS BERLEX LABORATORIES, INC. (US) 1998-08-27 WO disclosed
US-4273873-A BONDING SYNTHETIC FIBRINOLYTIC COMPOUND OR ENZYME UNITIKA LTD. (JP) 1981-06-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140142347-A1 PROCESS FOR PREPARING A SALT OF A SULFURIZED ALKYL-SUBSTITUTED HYDROXYAROMATIC COMPOSITION H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HTT, SEM1 FFAR1 1580/4885GABBR2 2878/4885GABBR1 2884/4885
US-12502367-B2 Oral baclofen solutions GABBR1, CA2, GABBR2 FFAR1 609/4885GABBR2 3/4885GABBR1 1/4885
US-20220233483-A1 ORAL BACLOFEN SOLUTIONS GABBR1, CA2, GABBR2 FFAR1 609/4885GABBR2 3/4885GABBR1 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.