Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.74 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.47 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30012190 | 1.00 | SLC6A3 (0.74) | SLC6A3SLC6A4SMN1; SMN2NPC1CASP3 | |
| SCHEMBL13824149 | 0.86 | SLC6A3 (0.55) | SLC6A3SLC6A4SMN1; SMN2NPC1CASP3 | |
| SCHEMBL13824199 | 0.86 | SLC6A3 (0.77) | SLC6A3SLC6A4SMN1; SMN2NPC1CASP3 | |
| SCHEMBL5533081 | 0.85 | PDCD1 (0.60) | SLC6A3SLC6A4TSHRPDCD1CD274 | |
| SCHEMBL29918042 | 0.85 | PDCD1 (0.60) | SLC6A3SLC6A4TSHRPDCD1CD274 | |
| SCHEMBL6627614 | 0.85 | SLC6A3 (1.00) | SLC6A3SLC6A4SMN1; SMN2NPC1CASP3 | |
| SCHEMBL20200106 | 0.84 | KDM4E (0.60) | SLC6A3SLC6A4NPC1CYP1A2CYP2D6 | |
| SCHEMBL29917415 | 0.84 | SLC6A3 (0.52) | SLC6A3SLC6A4PDCD1CD274SLC6A2 | |
| SCHEMBL29634134 | 0.83 | TSHR (0.53) | SLC6A3SLC6A4SMN1; SMN2RAB9ATSHR | |
| SCHEMBL19849652 | 0.83 | TSHR (0.53) | SLC6A3SLC6A4SMN1; SMN2RAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240246931-A1 | COMPOUNDS AS PD1/PD-L1 INHIBITORS AND METHODS THEREOF | Jubilant Prodel LLC (US) | 2024-07-25 | — | — | US | disclosed |
| EP-4326272-A1 | COMPOUNDS AS PD1/PD-L1 INHIBITORS AND METHODS THEREOF | Jubilant Prodel LLC (US) | 2024-02-28 | — | — | EP | disclosed |
| WO-2022224278-A1 | COMPOUNDS AS PD1/PD-L1 INHIBITORS AND METHODS THEREOF | Jubilant Prodel LLC (US) | 2022-10-27 | — | — | WO | disclosed |
| WO-2022224278-A1 | COMPOUNDS AS PD1/PD-L1 INHIBITORS AND METHODS THEREOF | Jubilant Prodel LLC (US) | 2022-10-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240246931-A1 | COMPOUNDS AS PD1/PD-L1 INHIBITORS AND METHODS THEREOF | CD274, PDCD1, PDCD1LG2 | SLC6A3 4372/4885SLC6A4 4854/4885SMN1; SMN2 3618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.