Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.52 |
| ▸ | CFTR | P13569 | 1/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | KLRK1 | P26718 | 3/20 | 0.43 |
| ▸ | MICA | Q29983 | 3/20 | 0.43 |
| ▸ | RAET1L | Q5VY80 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | APOB | P04114 | 2/20 | 0.42 |
| ▸ | MTTP | P55157 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29979725 | 0.87 | SLC6A3 (0.69) | SLC6A3SLC6A4CFTRPDK2BACE1 | |
| SCHEMBL10645473 | 0.87 | SLC6A3 (0.69) | SLC6A3SLC6A4CFTRPDK2BACE1 | |
| SCHEMBL18296883 | 0.84 | SLC6A3 (0.51) | SLC6A3SLC6A4PDK2PDCD1CD274 | |
| SCHEMBL24665233 | 0.84 | SLC6A3 (0.74) | SLC6A3SLC6A4PDK2PDCD1CD274 | |
| SCHEMBL2745460 | 0.84 | CYP2C8 (0.49) | BACE1KLRK1MICARAET1L | |
| SCHEMBL30012190 | 0.84 | SLC6A3 (0.74) | SLC6A3SLC6A4PDK2PDCD1CD274 | |
| SCHEMBL1885577 | 0.82 | PARP1 (0.50) | PDK2BACE1KLRK1MICARAET1L | |
| SCHEMBL5533081 | 0.82 | PDCD1 (0.60) | SLC6A3SLC6A4PDCD1CD274SLC6A2 | |
| SCHEMBL29918042 | 0.82 | PDCD1 (0.60) | SLC6A3SLC6A4PDCD1CD274SLC6A2 | |
| SCHEMBL20200106 | 0.81 | KDM4E (0.60) | SLC6A3SLC6A4PDCD1CD274SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111978200-B | Biphenylamide derivative, preparation method and application | 湖北省生物农药工程研究中心 | 2022-09-13 | — | — | CN | disclosed |