Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.56 |
| ▸ | CRHR1 | P34998 | 8/20 | 0.52 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24665390 | 0.85 | NTRK1 (0.52) | CRHR1NTRK1HPGDNPC1RAB9A | |
| SCHEMBL24665396 | 0.84 | HRH3 (0.42) | HRH3CRHR1NTRK1TRPV4 | |
| SCHEMBL24665392 | 0.84 | HRH3 (0.42) | HRH3CRHR1NTRK1TRPV4 | |
| SCHEMBL19541088 | 0.81 | PDK2 (0.68) | CRHR1NTRK1HPGDNPC1RAB9A | |
| SCHEMBL22845271 | 0.75 | HPGD (0.62) | HRH3CRHR1NTRK1HPGDNPC1 | |
| SCHEMBL10211612 | 0.75 | HRH3 (0.65) | HRH3TEAD1 | |
| SCHEMBL1846824 | 0.74 | CRHR1 (0.72) | CRHR1 | |
| SCHEMBL1846823 | 0.74 | CRHR1 (0.72) | CRHR1 | |
| SCHEMBL14410200 | 0.73 | MEN1 (0.55) | TRPV4 | |
| SCHEMBL20794986 | 0.73 | MCHR1 (0.58) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11787769-B2 | Inhibitors of influenza viral entry | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2023-10-17 | — | — | US | disclosed |
| US-20220267275-A1 | Inhibitors of Influenza Viral Entry | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2022-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11787769-B2 | Inhibitors of influenza viral entry | NAAA, AADAC, FURIN | HRH3 183/4885CRHR1 3524/4885NTRK1 4485/4885 |
| US-20220267275-A1 | Inhibitors of Influenza Viral Entry | NAAA, AADAC, FURIN | HRH3 183/4885CRHR1 3524/4885NTRK1 4485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.