Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 20/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24668656 | 0.84 | CA2 (0.38) | CA2 | |
| SCHEMBL8824490 | 0.67 | TNKS2 (0.37) | CA2 | |
| SCHEMBL30067654 | 0.67 | CA2 (0.54) | CA2CA12CA1CA4CA6 | |
| SCHEMBL1805395 | 0.67 | CA2 (1.00) | CA2CA12CA1CA4CA6 | |
| SCHEMBL7618628 | 0.66 | CA2 (0.56) | CA2CA12CA1CA5ACA9 | |
| SCHEMBL9325032 | 0.66 | TNKS2 (0.36) | CA2 | |
| SCHEMBL5436203 | 0.66 | CA2 (0.64) | CA2CA12CA1CA4CA6 | |
| SCHEMBL24670388 | 0.66 | CA2 (0.50) | CA2 | |
| SCHEMBL24668652 | 0.64 | CA2 (0.40) | CA2 | |
| SCHEMBL21586454 | 0.63 | CA2 (0.58) | CA2CA12CA1CA6CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022187693-A1 | COVALENT CDK2-BINDING COMPOUNDS FOR THERAPEUTIC PURPOSES | UMBRA THERAPEUTICS INC. (US) | 2022-09-09 | — | — | WO | disclosed |