Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP12 | P39900 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MELK | Q14680 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5434012 | 0.67 | CA2 (0.65) | CA2 | |
| SCHEMBL24670392 | 0.67 | CA2 (0.44) | CA2 | |
| SCHEMBL24668653 | 0.64 | CA2 (0.50) | CA2 | |
| SCHEMBL14848498 | 0.63 | ALDH1A1 (0.40) | MMP2MMP12ALDH1A1MELK | |
| SCHEMBL21586454 | 0.62 | CA2 (0.58) | CA2ALDH1A1 | |
| SCHEMBL30067654 | 0.62 | CA2 (0.54) | CA2ALDH1A1 | |
| SCHEMBL7618628 | 0.61 | CA2 (0.56) | CA2ALDH1A1 | |
| SCHEMBL24668655 | 0.60 | CA2 (0.34) | CA2 | |
| SCHEMBL16377626 | 0.60 | APP (0.38) | MMP2MMP12ALDH1A1MELK | |
| SCHEMBL6869002 | 0.60 | NLRP3 (0.45) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022187693-A1 | COVALENT CDK2-BINDING COMPOUNDS FOR THERAPEUTIC PURPOSES | UMBRA THERAPEUTICS INC. (US) | 2022-09-09 | — | — | WO | disclosed |